RIP2 (RIPK2) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blotting: 1/1000. Immunohistochemistry: 1/50 - 1/100.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between aa 458 - 488 from the C-terminal region of human RIPK2.
Specificity	This antibody reacts to RIP2 (RIIPK2).
Isotype	Ig
Formulation	PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	receptor interacting serine/threonine kinase 2
Database Link	Entrez Gene 192656 MouseEntrez Gene 8767 Human UniProt ID O43353
Background	RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Synonyms	CARDIAK, RICK, RIP2, RIP-2, Receptor-interacting protein 2
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Neurotrophin signaling pathway, NOD-like receptor signaling pathway

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