CORIN Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Peptide ELISA: 1/1000. Western blot: 1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 459-490 amino acids from the Central region of human CORIN.
Specificity	This antibody detects CORIN at Center.
Formulation	PBS with 0.09% (W/V) sodium azide State: Liquid Ig fraction
Concentration	lot specific
Purification	Purified through a protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	corin, serine peptidase
Database Link	Entrez Gene 53419 MouseEntrez Gene 10699 Human UniProt ID Q9Y5Q5
Background	CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. This protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
Synonyms	CRN, TMPRSS10, Pro-ANP-converting enzyme, ATC2
Note	Molecular weight: 116565 Da
Reference Data
Protein Families	Druggable Genome, Protease, Transmembrane

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