Glutathione S Transferase theta 1 (GSTT1) (+GSTT4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/500 - 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	This antibody detects endogenous levels of GSTT1/4 protein. (region surrounding Arg31)
Formulation	Phosphate buffered saline (PBS), pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide
Concentration	1.0 mg/ml
Purification	Affinity-chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 30 kDa
Gene Name	glutathione S-transferase theta 1
Database Link	Entrez Gene 2952 Human UniProt ID P30711
Background	The GST superfamily is made up of several subfamilies. Glutathione Stransferase P (GSTP1) belongs to the π subfamily and is involved in the conjugation of reduced glutathione to a variety of endogenous and exogenous hydrophobic electrophiles. Glutathione S-transferase μ 1 (GSTM1) is a cytoplasmic liver protein belonging to the μ family and has the same basic functions as GSTP1-1. Glutathione S-transferase θ 1 (GSTT1), a cytoplasmic homodimer belonging to the θ family, is expressed in erythrocytes. It is active in the reduced glutathione conjugation and also displays glutathione peroxidase activity with cumene hydroperoxide.
Synonyms	Glutathione S-transferase theta-1, GST class-theta-1, Glutathione transferase T1-1
Reference Data
Protein Pathways	Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450

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