ITPR2 (1152-1164) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Canine, Human, Mouse, Rat, Monkey
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of human ITPR2
Specificity	This antibody detects IP3 receptor 2 / ITPR2 (Internal).
Formulation	Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	inositol 1,4,5-trisphosphate receptor type 2
Database Link	Entrez Gene 16439 MouseEntrez Gene 81678 RatEntrez Gene 3709 Human UniProt ID Q14571
Background	ITPR2 / IP3 Receptor Type 2 belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling.
Synonyms	Type 2 InsP3 receptor, IP3R2
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Alzheimer's disease, Calcium signaling pathway, Gap junction, GnRH signaling pathway, Long-term depression, Long-term potentiation, Oocyte meiosis, Phosphatidylinositol signaling system, Vascular smooth muscle contraction

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