IL10 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, FN, IHC, WB
Recommend Dilution	IMmunohistochemistry on frozen sections. Immunoassays. Western blot. Functional assays: Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. The typical starting working dilution for cll staining is 1:10.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	The antibody reacts with human Interleukin-10 (IL-10) of both natural and recombinant origin. It inhibits the biological activity of natural and recombinant human IL-10. The antigen specificity was further assessed by ELISA. No cross reactivities with other cytokines have been detected.
Isotype	IgG
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein A
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Gene Name	interleukin 10
Database Link	Entrez Gene 3586 Human UniProt ID P22301
Background	IL-10 is a pluripotent cytokine with important immunosuppressive actions: it can inhibit cytokines involved in the Th1 response such as IL-2, Interferon gamma and also inhibits the production of pro-inflammatory cytokines such as IL-1, IL-6, IL-8 and TNF-alpha.
Synonyms	IL-10, CSIF, TGIF
Reference Data

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