ZAP70 Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/32000 (Detection limit). Western blot: 0.3-1 µg/ml. Detects a band of Approx 70kDa in lysates of cell lines Jurkat and Molt4.
Reactivity	Bovine, Canine, Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_001070.2.
Specificity	This antibody is expected to recognize isoform 1 (NP_001070.2) only.
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	69.9 kDa (NP_001070.2).
Gene Name	zeta chain of T cell receptor associated protein kinase 70kDa
Database Link	Entrez Gene 7535 Human UniProt ID P43403
Background	ZAP-70 is a 70kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.
Synonyms	ZAP-70, ZAP 70, SRK
Reference Data

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