JNK2 (MAPK9) (217-230) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA:  1/32000 (Detection limit).  Western blot: 0.5-1.5µg/ml. Detects a band of Approx 48kDa in Human Brain (Cerebellum) and Mouse Brain lysates.
Reactivity	Canine, Human, Mouse, Porcine, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-EMVLHKVLFPGRDY, from the internal region of the protein sequence according to NP_620708.1; NP_620709.1.
Specificity	This antibody is expected to recognize isoforms beta 1 and beta 2 of JNK2 (NP_620708.1, NP_620709.1).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	48.3 kDa (NP_620709.1).
Gene Name	mitogen-activated protein kinase 9
Database Link	Entrez Gene 5601 Human UniProt ID P45984
Background	c-Jun amino terminal kinases (JNKs) are MAP kinase family members that differ from other MAP kinases in that they are phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
Synonyms	JNK-55, PRKM9, MAP kinase 9
Reference Data

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