HERC4 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blotting (0.2 - 1 µg/ml).
Reactivity	Bovine, Canine, Human, Mouse, Rat, African clawed frog
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to the N terminal region of human HERC4, Isoform 5
Formulation	State: Aff - Purified State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Immunoaffinity column
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	HERC4: 13 kDa
Gene Name	HECT and RLD domain containing E3 ubiquitin protein ligase 4
Database Link	Entrez Gene 26091 Human UniProt ID Q5GLZ8
Background	HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.
Synonyms	KIAA1593
Reference Data

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