Collagen XVII (COL17A1) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	Peptidfe ELISA: 1/1000. Western blot: ~1/2000. Immunohistochemistry on Paraffin Sections: 1/50-1/100. Flow Cytometry: ~1/125.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide selected between amino acids 475 and 504 from the Central region of human COL17A1
Specificity	This antibody reacts to COL17A1.
Isotype	Ig
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	150419 Da
Gene Name	collagen type XVII alpha 1
Database Link	Entrez Gene 1308 Human UniProt ID Q9UMD9
Background	COL17A1 encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.
Synonyms	COL17A1, BP180, BPAG2, Bullous pemphigoid antigen 2, LAD-1, LABD97
Reference Data
Protein Families	Transmembrane

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