Dopamine beta Hydroxylase (DBH) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: ~1/2000. Immunofluorescence: 1/10-/50. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 27-56 amino acids from the N-terminal region of Human DBH.
Specificity	This antibody recognizes Human DBH (N-term).
Isotype	Ig
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	dopamine beta-hydroxylase
Database Link	Entrez Gene 1621 Human UniProt ID P09172
Background	The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq].
Synonyms	DBH, Dopamine beta-monooxygenase, DBM, DOPO
Note	Molecular Weight: 69065 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	Metabolic pathways, Tyrosine metabolism

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