MYSM1 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	Flow cytometry: 1/10-1/50. Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 118-147aa) of human MYSM1
Specificity	This antibody recognizes MYSM1 at N-term.
Isotype	Ig
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Myb like, SWIRM and MPN domains 1
Database Link	Entrez Gene 320713 MouseEntrez Gene 114803 Human UniProt ID Q5VVJ2
Background	Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Synonyms	KIAA1915
Note	Molecular Weight: 95032 Da
Reference Data
Protein Families	Protease

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