SPRR1B (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin sections: 1/50-1/100. Western blot: 1/1000. Enzyme immunoassay: 1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 63-89aa) of human SPRR1B / Cornifin-B
Specificity	This antibody recognizes SPRR1B / Cornifin-B at C-term.
Isotype	Ig
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	small proline rich protein 1B
Database Link	Entrez Gene 6699 Human UniProt ID P22528
Background	SPRR1B/Cornifin-B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Cornifin-B can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
Synonyms	SPR-IB
Note	Molecular Weight: 9888 Da
Reference Data

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