PADI1 (specific epitope) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/200-1/1000. Immunohistochemistry: 1/200-1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from a domain specific for Human Peptidylarginine Deiminase type 1 protein
Specificity	This antibody reacts with Human PADI1. Cross reactivity with other PADI isoforms was not yet tested.
Formulation	0.1M Tris, 0.1M Glycine and 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store the antibody at -20°C. Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer Avoid repeated freezing and thawing.
Gene Name	peptidyl arginine deiminase 1
Database Link	Entrez Gene 29943 Human UniProt ID Q9ULC6
Background	Peptidylarginine deiminases (PADs) convert arginine residues in proteins into citrullines. They are suspected to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis and possibly in regulation of gene expression through histone modification. In humans, five isoforms encoded by the genes PADI1-4, 6 are known so far.
Synonyms	PDI1, PAD1, HPAD10
Reference Data

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