VPS39 pSer39 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/500-1/2000. Immunohistochemistry: 1/50-1/2000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from an internal domain of Human Vam6 protein
Specificity	Reacts with Human VPS39 102 kDa protein. Cross reacts with Mouse and other species.
Formulation	State: Serum State: Lyophilized powder Preservative: None
Reconstitution Method	Restore in distilled water.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store the antibody at -20°C. Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	VPS39, HOPS complex subunit
Database Link	Entrez Gene 23339 Human UniProt ID Q96JC1
Background	VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-b response by coupling the TGF-b receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.
Synonyms	KIAA0770, VAM6, Vam6/Vps39-like protein
Reference Data

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