beta 2 Microglobulin (B2M) Mouse Monoclonal Antibody [Clone ID: B1G6]

Specifications

Product Data
Clone Name	B1G6
Applications	FC, IF, IHC
Recommend Dilution	Purification of the HLA antigens associated with Beta 2-Microglobulin. Fluorescence Microscopy or Flow Cytometry: 2 µl/5x105 cells/test. Immunohistochemistry on Frozen Sections or Cell Smears: Working dilution 1/25-1/50.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human Beta 2-Microglobulin
Specificity	Specific for Human beta 2-Microglobulin (MW 12 kDa). Recognizes the HLA-beta 2-Microglobulin complex, free or associated with the membrane. Does not react with other species. The exact epitope for the antibody has not been mapped.
Isotype	IgG2a
Formulation	PBS State: Purified State: Lyophilized purified IgG fraction Stabilizer: 1 mg/ml BSA Preservative: None
Reconstitution Method	Restore with 1.0 ml distilled water
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Addition of 0.09% (w/v) Sodium Azide is recommended for storage up to one month at 2-8°C. Avoid repeated freezing and thawing.
Gene Name	beta-2-microglobulin
Database Link	Entrez Gene 567 Human UniProt ID P61769
Background	Beta-2 Microglobulin non-covalently associates with the 44 kDa alpha chain to form the HLA Class I antigen complex. Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.
Synonyms	B2M, Beta-2 microglobulin, Beta 2 microglobulin
Reference Data

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