Cortisol Mouse Monoclonal Antibody [Clone ID: BDI410]

Specifications

Product Data
Clone Name	BDI410
Applications	ELISA
Recommend Dilution	Suitable for ELISA.
Host	Mouse
Clonality	Monoclonal
Immunogen	Cortisol-3 CMO-BgG.
Specificity	This antibody reacts with Cortisol. Cross Reactivity: Corticosterone: 45% Progesterone: 9% Deoxycortisol: < 2% Dexamethazone: < 2% Estrone (E1): < 0.01% Estriol (E3): < 0.01% Testosterone: < 0.01%
Isotype	IgG
Formulation	0.05 M Phosphate, 0.85% Sodium Chloride, pH 7.15 State: Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. In plasma a majority of cortisol is bound with high affinity to corticosteroid binding globulin (CBG or transcotin). Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.
Synonyms	Hydrocortisone
Reference Data

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