Insulin (INS) Mouse Monoclonal Antibody [Clone ID: IN-05]

Specifications

Product Data
Clone Name	IN-05
Applications	ELISA, FN, IHC, R
Recommend Dilution	ELISA. RIA. Immunocytochemistry. Functional Application. Immunohistochemistry on Paraffin Sections.
Reactivity	Bovine, Human, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Porcine Insulin
Specificity	The antibody reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas; it is also present in tumors of B cell origin such as insulinoma. The antibody IN-05 blocks binding of Insulin to the receptor.
Isotype	IgG1
Formulation	Phosphate buffered saline (PBS), pH~7.3 with 15 mM Sodium Azide as presrevative. State: Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Concentration	lot specific
Purification	Affinity Chromatography on Protein A.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	insulin
Database Link	Entrez Gene 3630 Human UniProt ID P01308
Background	Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.
Synonyms	INS
Reference Data

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