IL1 Receptor II (IL1R2) Mouse Monoclonal Antibody [Clone ID: 49/20]

Specifications

Product Data
Clone Name	49/20
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	R-DNA. Human interleukin-1 soluble receptor, type 1 expressed in insect cell line Sf.
Specificity	This antibody reacts to Interleukin 1 Receptor Type I. Does not react with rmIL-1 RI or rhIL-1 RII in either Western blotting or ELISA.
Formulation	PBS buffer, pH 7.2 with 5% trehalose State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at 2-8°C. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	interleukin 1 receptor type 2
Database Link	Entrez Gene 7850 Human UniProt ID P27930
Background	IL1 Receptor II is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
Synonyms	Interleukin-1 receptor type II, IL-1R-2, IL-1R-beta, CDw121b, IL1RB
Reference Data

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