Aldosterone Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: Used in a competitive ELISA with 400 ng of Aldosterone-3-BSA per well. Immunohistochemistry on Frozen Sections: Use at 1/25-1/200 depending on detection system. Overnight incubation at 4°C is recommended.
Host	Rabbit
Clonality	Polyclonal
Immunogen	Aldosterone-3-CMO-BSA
Specificity	This antibody is specific for Aldosterone, a hormone produced by the adrenal glands that helps regulate blood pressure through increasing both the release of potassium and the uptake of water and sodium by the kidneys. Cross-Reactivity: Aldosterone: 100% Androstenedione: < 1% Corticosterone: < 1% DHEA: < 1% Desoxycorticosterone: < 1%
Isotype	IgG
Formulation	PBS buffer containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It acts in the kidney promoting the reabsorption of sodium ions (Na+) into the blood. Water follows the salt and this helps maintain normal blood pressure. It also acts on sweat glands to reduce the loss of sodium in perspiration and taste cells to increase the sensitivity of the taste buds to sources of sodium.
Note	This antibody has been cross-absorbed with BSA.
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.