SYNPR Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC
Recommend Dilution	Immunofluorescence Microscopy: 1/100-200 for 1 h at RT. Immunohistochemistry on Frozen Sections.
Reactivity	Human, Mouse, Rat
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic C-terminal peptide CHSSGQRYLSDPMEKHS (corresponding to a part of the cytoplasmic carboxy terminus) conjugated to KLH.
Specificity	Antiserum reacts specifically with Synaptoporin present in synaptic vesicles. No cross-reaction with pantophysin and the closely related protein Synaptophysin (additional members of the small polypeptide family typical for transport vesicles).
Formulation	State: Serum State: Liquid Stabilized antiserum with 0.09% Sodium Azide and 0.5% BSA
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	synaptoporin
Database Link	Entrez Gene 66030 RatEntrez Gene 72003 MouseEntrez Gene 132204 Human UniProt ID Q8TBG9
Background	SYNPR( Synaptoporin) is a component of the synaptic vesicle membrane and thought to play an important role in synaptic vesicle trafficking. It is highly homologous to Synaptophysin 1 yet it differs in expression. Synaptophysin 1 is ubiquitiously expressed, SYNPR is concentrated in the mossy fibre synapses of the hippocampus. Synaptoporin, an intrinsic membrane protein of small synaptic vesicles, probably functions as vesicular channel protein.
Synonyms	MGC26651, Synaptophysin-2
Reference Data
Protein Families	Secreted Protein, Transmembrane

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