SAMHD1 Mouse Monoclonal Antibody [Clone ID: OTI1F6]
CAT#: CF501953
Carrier-free (BSA/glycerol-free) SAMHD1 mouse monoclonal antibody, clone OTI1F6 (formerly 1F6)
Formulation: Standard
View other "OTI1F6" antibodies (4)
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CNY 3999.00
| Cited in 18 publications. |
Specifications
| Product Data | |
| Clone Name | OTI1F6 |
| Applications | FC, IF, WB |
| Recommend Dilution | WB 1:500~2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Monkey |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell. |
| Isotype | IgG1 |
| Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 72.0 kDa |
| Gene Name | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 |
| Database Link | |
| Background | This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq]. COMPLETENESS: complete on the 3' end. |
| Synonyms | CHBL2; DCIP; HDDC1; MOP-5; SBBI88 |
| Reference Data | |
Citations (18)
| The use of this Antibodies has been cited in the following citations: |
|---|
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PERV induces CXCL10 in human monocytes and monocyte-derived primary cells.
,null,
Intervirology
,PubMed ID 36382641
[SAMHD1]
|
|
Degradation of SAMHD1 Restriction Factor Through Cullin-Ring E3 Ligase Complexes During Human Cytomegalovirus Infection
,null,
Frontiers in Cellular and Infection Microbiology
,PubMed ID 32850489
[SAMHD1]
|
|
Human interleukin-34-derived macrophages have increased resistance to HIV-1 infection.
,null,
Cytokine
,PubMed ID 30241016
[SAMHD1]
|
|
The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression
,null,
eLife
,PubMed ID 30132758
[SAMHD1]
|
|
DNA damage response signaling does not trigger redistribution of SAMHD1 to nuclear foci.
,null,
Biochemical and biophysical research communications
,PubMed ID 29614270
[SAMHD1]
|
|
DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1
,null,
Scientific Reports
,PubMed ID 29515139
[SAMHD1]
|
|
A central role for PI3K-AKT signaling pathway in linking SAMHD1-deficiency to the type I interferon signature
,null,
Scientific Reports
,PubMed ID 29311560
[SAMHD1]
|
|
Brain Microglial Cells Are Highly Susceptible to HIV-1 Infection and Spread
,null,
AIDS Research and Human Retroviruses
,PubMed ID 28486838
[SAMHD1]
|
|
The expression profile of sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) in feline tissues.
,null,
Veterinary immunology and immunopathology
,PubMed ID 29249320
[SAMHD1]
|
|
Imaging HIV-1 Genomic DNA from Entry through Productive Infection
,null,
Journal of Virology
,PubMed ID 28250118
[SAMHD1]
|
|
TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes
,null,
Retrovirology
,PubMed ID 27905985
[SAMHD1]
|
|
Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1.
,null,
Virology
,PubMed ID 27179347
[SAMHD1]
|
|
Phosphorylation of murine SAMHD1 regulates its antiretroviral activity
,null,
Retrovirology
,PubMed ID 26667483
[SAMHD1]
|
|
Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers
,null,
PLoS Pathogens
,PubMed ID 26067651
[SAMHD1]
|
|
HIV Type 1 Infection of Plasmacytoid and Myeloid Dendritic Cells Is Restricted by High Levels of SAMHD1 and Cannot be Counteracted by Vpx
,null,
AIDS Research and Human Retroviruses
,PubMed ID 23924154
[SAMHD1]
|
|
SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells
,null,
PLoS ONE
,PubMed ID 24586870
[SAMHD1]
|
|
Inhibition of CUL4A Neddylation Causes a Reversible Block to SAMHD1-Mediated Restriction of HIV-1
,null,
Journal of Virology
,PubMed ID 23986575
[SAMHD1]
|
|
Restriction of diverse retroviruses by SAMHD1
,null,
Retrovirology
,PubMed ID 23497255
[SAMHD1]
|
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Resources
| 抗体相关资料 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| TA501953 | SAMHD1 mouse monoclonal antibody, clone OTI1F6 (formerly 1F6) |
CNY 1999.00 |
|
| TA501953AM | SAMHD1 mouse monoclonal antibody, clone OTI1F6 (formerly 1F6), Biotinylated |
CNY 3990.00 |
|
| TA501953BM | SAMHD1 mouse monoclonal antibody, clone OTI1F6 (formerly 1F6), HRP conjugated |
CNY 3990.00 |
|
| TA501953S | SAMHD1 mouse monoclonal antibody, clone OTI1F6 (formerly 1F6) |
CNY 800.00 |
