Heme oxygenase 2 (HMOX2) Mouse Monoclonal Antibody [Clone ID: OTI1C2]

Specifications

Product Data
Clone Name	OTI1C2
Applications	FC, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HMOX2(NP_002125) produced in HEK293T cell.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35.9 kDa
Gene Name	heme oxygenase 2
Database Link	NP_002125 Entrez Gene 15369 MouseEntrez Gene 79239 RatEntrez Gene 3163 Human UniProt ID P30519
Background	Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus. [provided by RefSeq, Jul 2008]
Synonyms	HO-2
Reference Data
Protein Families	Transmembrane
Protein Pathways	Porphyrin and chlorophyll metabolism

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