APMAP Mouse Monoclonal Antibody [Clone ID: OTI4F6]

Specifications

Product Data
Clone Name	OTI4F6
Applications	IHC, Simple Western, WB
Recommend Dilution	WB 1:500~2000, IHC 1:150; Simple Western 1:20-1:50
Reactivity	Human, Dog, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human C20orf3(NP_065392) produced in HEK293T cell.
Isotype	IgG2b
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46.3 kDa
Gene Name	adipocyte plasma membrane associated protein
Database Link	NP_065392 Entrez Gene 71881 MouseEntrez Gene 366227 RatEntrez Gene 608089 DogEntrez Gene 704948 MonkeyEntrez Gene 57136 Human UniProt ID Q9HDC9
Background	CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM]
Synonyms	BSCv; C20orf3
Reference Data
Protein Families	Transmembrane

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