Frataxin (FXN) Mouse Monoclonal Antibody [Clone ID: OTI1C12]

Specifications

Product Data
Clone Name	OTI1C12
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:1000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human FXN(NP_000135) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	18.8 kDa
Gene Name	frataxin
Database Link	NP_000135 Entrez Gene 2395 Human UniProt ID Q16595
Background	This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms	CyaY; FA; FARR; FRDA; X25
Reference Data
Protein Families	Druggable Genome

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