p75 NGF Receptor (NGFR) Mouse Monoclonal Antibody [Clone ID: OTI8F1]

Specifications

Product Data
Clone Name	OTI8F1
Applications	FC, WB
Recommend Dilution	WB 1:500, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human Ngfr (NP_002498) produced in HEK293T cell.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45.18 kDa
Gene Name	nerve growth factor receptor
Database Link	NP_002498 Entrez Gene 18053 MouseEntrez Gene 24596 RatEntrez Gene 4804 Human UniProt ID P08138
Background	Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
Synonyms	CD271; Gp80-LNGFR; p75(NTR); p75NTR; TNFRSF16
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway

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