TDP43 (TARDBP) Mouse Monoclonal Antibody [Clone ID: OTI4C1]

Specifications

Product Data
Clone Name	OTI4C1
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment of Human TARDBP (NP_031401) produced in Ecoli.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	44.7 kDa
Gene Name	TAR DNA binding protein
Database Link	NP_031401 Entrez Gene 230908 MouseEntrez Gene 23435 Human UniProt ID Q13148
Background	The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
Synonyms	ALS10; TDP-43
Reference Data
Protein Families	Transcription Factors

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