Dystonin (DST) Human Monoclonal Antibody [Clone ID: H10D-Hy-8B]

Specifications

Product Data
Clone Name	H10D-Hy-8B
Applications	IF, IHC, WB
Recommend Dilution	WB, IF, IHC frozen section. Usage recommendation: *This monoclonal antibody may be used between 5-20 μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before using.
Reactivity	Human
Host	Human
Clonality	Monoclonal
Immunogen	EBV cell clones derived from PBMC of patients with the typical clinical, histologic, immunopathologic criteria of Bullous Pemphigoid
Isotype	IgG4
Formulation	Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8. Coupled: 100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol. State: Purified
Concentration	lot specific
Purification	QMA Hyper D ion exchangechromatography
Conjugation	Unconjugated
Storage Condition	-20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing.
Gene Name	dystonin
Database Link	Entrez Gene 667 Human UniProt ID Q03001
Background	Bullous pemphigoid is an acquired blistering skin disease associated with production of IgG autoantibodies to the BP antigen. Antibodies-producing cells were established by EBV infection of CD40-activated PBMCs. These antibodies recognize different epitopes of BPAg1. (Peyron E. et al.,.J Immunol,1994,153, 1333)
Synonyms	Hemidesmosomal plaque protein, Dystonia musculorum protein, BPA, Bullous pemphigoid antigen, DST, BPAG1, DMH, DT, KIAA0728
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.