Glycophorin A (GYPA) Mouse Monoclonal Antibody [Clone ID: JC159]

Specifications

Product Data
Clone Name	JC159
Applications	IHC
Recommend Dilution	Immunohistochemistry on formalin fixed paraffin embedded sections: use a dilution of 1:25-1:50 in an ABC method (30 minutes at room temperature). Recommended positive control: Tonsil
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Formalin fixed membrane from a Hairy cell leukemia
Specificity	This antibody reacts with glycophorin A in the erythroid cells. It can stain erythroid cells at all stages of development and differentiation. The antibody may be useful in the identification of neoplastic erythroblasts. Cellular Localization: Cell membrane
Isotype	IgG1
Formulation	State: Supernatant State: Ttissue Culture Supernatant Preservative: Less than 0.1% Sodium Azide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	glycophorin A (MNS blood group)
Database Link	Entrez Gene 2993 Human UniProt ID P02724
Background	Glycophorins A (GPA) and B (GPB) are single pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.
Synonyms	Glycophorin-A, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein
Reference Data

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