CD11b Rat Monoclonal Antibody [Clone ID: M1/70.15]

Specifications

Product Data
Clone Name	M1/70.15
Applications	FC
Recommend Dilution	Flow cytometry: Neat. Positive control: mouse peritoneal macrophages.
Reactivity	Human, Mouse, Rabbit
Host	Rat
Clonality	Monoclonal
Immunogen	T cell enriched splenocytes from B10 mice
Specificity	This antibody recognises the CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. Clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue (4).
Isotype	IgG2b
Formulation	0.09% Sodium Azide, 1% Bovine Serum Albumin Label: Biotin State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Database Link	UniProt ID P05555
Background	The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages.
Synonyms	ITGAM, CR3A, CR-3 alpha chain, Integrin alpha-M, MAC1
Reference Data

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