Msr1 Rat Monoclonal Antibody [Clone ID: 2F8]

CAT#: SM029FT

Msr1 rat monoclonal antibody, clone 2F8, FITC



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CNY 2,570.00


货期*
4周

规格
    • 25 ug

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Specifications

Product Data
Clone Name 2F8
Applications FC
Recommend Dilution Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
Use The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen RAW264 cell line.
Specificity This antibody recognises the Murine Scavenger Receptor class A (SRA), type I and II, also known as CD204. Clone 2F8 recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain (Daugherty et al. 2000).
Formulation PBS containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Label: FITC
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Label: Fluorescein Isothiocyanate Isomer 1
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation FITC
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Gene Name macrophage scavenger receptor 1
Background CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion.
Recent research shows that clone 2F8 recognises an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
Synonyms MSR1, SCARA1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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