CD49b (ITGA2) Mouse Monoclonal Antibody [Clone ID: AK7]

Specifications

Product Data
Clone Name	AK7
Applications	FC
Recommend Dilution	Flow cytometry: 1/50 - 1/100; use 10 µl of the suggested working dilution to label 10e6 cells in 100µl. Immunohistochemistry on frozen sections: 1/500 - 1/1000. Recommended positive control tissue: Tonsil.
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.
Specificity	This antibody recognises the integrin alpha2 subunit, which is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, endothelial cells, monocytes and most adherent cell lines. Cross reacts with Cynomolgus monkey (3), Baboon and Rhesus monkey.
Isotype	IgG1
Formulation	PBS containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha 2
Database Link	Entrez Gene 3673 Human UniProt ID P17301
Background	CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50% of monocytes and most adherent cell lines. MCA743 inhibits cell attachment to collagen.
Synonyms	Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor
Reference Data

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