Integrin alpha 4 (ITGA4) Mouse Monoclonal Antibody [Clone ID: 44H6]

Specifications

Product Data
Clone Name	44H6
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/40 diluted antibody to label 100 µl of human whole peripheral blood. Immunohistochemistry on Frozen Sections (1/50-1/100) (Overnight incubation recommended). Recommended Positive Control Tissue: Human Tonsil.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	HOON pre-B leukaemia cell line. Spleen cells from immunised BALB/c mice were fused with cells of the SP2.0-Ag14 mouse myeloma cell line.
Specificity	This antibody recognises CD49d, also known as Integrin alpha 4, which associates with either CD29 (integrin beta 1) or integrin beta 7. 44H6 induces homotypic aggregation.
Isotype	IgG1
Formulation	PBS, pH 7.2 containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Ion Exchange Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	integrin subunit alpha 4
Database Link	Entrez Gene 3676 Human UniProt ID P13612
Background	CD49d is a 150kD molecule, which may be cleaved to 80kD and 70kD fragments. It is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin.
Synonyms	Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4
Reference Data

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