CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: SN6]

Specifications

Product Data
Clone Name	SN6
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
Reactivity	Equine, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Partially purified cell membrane antigens from fresh leukaemia cells
Specificity	This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kD subunits.
Isotype	IgG1
Formulation	PBS, pH 7.4, containing 0.09% sodium azide as preservative and 1% BSA as stabilizer. Label: PE State: Lyophilized purified IgG fraction. Label: R. Phycoerythrin (RPE)
Reconstitution Method	Restore with 1.0 ml distilled water.
Purification	Affinity Chromatography on Protein G.
Conjugation	PE
Storage Condition	Prior to and following reconstitution store the antibody undiluted at 2-8°C. DO NOT FREEZE! This Product is photosensitive and should be protected from light.
Gene Name	endoglin
Database Link	Entrez Gene 2022 Human UniProt ID P17813
Background	CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Synonyms	ENG, END, HHT1, ORW, ORW1
Reference Data

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