T Cell Receptor (TCR) alpha/beta (alpha chain) Mouse Monoclonal Antibody [Clone ID: 3A8]

Specifications

Product Data
Clone Name	3A8
Applications	IHC, IP
Recommend Dilution	Immunoprecipitation. Immunohistochemistry on Frozen Sections. Not suitable for Flow Cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody reacts with the alpha chain constant region found on all alpha beta TCR bearing T-lymphocytes. It reacts with 92-98% of all CD3+ peripheral blood lymphocytes. Negative Species: Mouse, Rat.
Isotype	IgG2a
Formulation	PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 0.5% BSA Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Database Link	UniProt ID P01848
Background	TCR (T cell antigen receptor) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 coreceptors are also required for efficient signal transduction through the TCR.
Synonyms	TCRA, TCRB, T-Cell Receptor alpha, T-Cell Receptor beta, T-Cell Receptor alpha beta
Reference Data

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