Cardiac Troponin I (TNNI3) Mouse Monoclonal Antibody [Clone ID: 110 (10F4)]

Specifications

Product Data
Clone Name	110 (10F4)
Applications	ELISA, WB
Recommend Dilution	Suitable for ELISA and Western blotting.
Reactivity	Bovine, Canine, Feline, Goat, Human, Porcine, Rabbit, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human Cardiac Troponin I.
Specificity	This antibody is specific for amino acids 34-37 of Troponin I from Human heart. There is no cross-reactivity with skeletal muscle Troponin I.
Isotype	IgG2a
Formulation	PBS pH 7.4, containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	troponin I3, cardiac type
Database Link	Entrez Gene 7137 Human UniProt ID P19429
Background	Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. E.g. TnI inhibits ATP-ase activity of acto-myosin. TnT and TnI are presented in cardiac muscles in different forms than in skeletal muscles. Only one tissue-specific isoform of TnI is described for cardiac muscle tissue (cTnI). cTnI is expressed only in myocardium
Synonyms	TNNI3, TNNC1
Reference Data

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