C5R1 (C5AR1) Mouse Monoclonal Antibody [Clone ID: P12/1]

Specifications

Product Data
Clone Name	P12/1
Applications	FC
Recommend Dilution	Flow Cytometry: Use 10 µl of 1/10 diluted antibody solution to label 106 cells in 100 µl.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	C5aR - peptide: Met1 - Asn31
Specificity	The antibody recognizes the N-terminal extracellular segment of the Human CD88 cell surface antigen (C5aR). Clone P12/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31). This CD88 antibody, clone P12/1 does not inhibit the binding of C5a to its receptor.
Isotype	IgG2a
Formulation	PBS Label: FITC State: Liquid purified IgG fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide Label: Fluorescein Isothiocyanate Isomer 1
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	FITC
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Gene Name	complement component 5a receptor 1
Database Link	Entrez Gene 728 Human UniProt ID P21730
Background	CD88 is expressed by peripheral blood granulocytes and monocytes. Binding of C5a to CD88 leads to cellular activation, including chemotaxis.
Synonyms	C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1
Reference Data

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