Granzyme B (GZMB) Mouse Monoclonal Antibody [Clone ID: GB10]

Specifications

Product Data
Clone Name	GB10
Applications	ELISA
Recommend Dilution	ELISA: 1 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human Granzyme B. Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Specificity	This antibody recognises the serine protease Granzyme B. This antibody has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (SM1806P) as capture reagent.
Isotype	IgG1
Formulation	PBS containing 0.001% Thiomersal Label: Biotin State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Biotin
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	granzyme B
Database Link	Entrez Gene 3002 Human UniProt ID P10144
Background	Ganzyme B which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.
Synonyms	Granzyme-2, CGL1, CTSGL1, CSPB, CTLA1, CTLA-1, GRB, SECT, Fragmentin-2
Reference Data

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