Alkaline Phosphatase (ALPP) Mouse Monoclonal Antibody [Clone ID: H17E2]

Specifications

Product Data
Clone Name	H17E2
Applications	ELISA, FC, IHC
Recommend Dilution	ELISA. Flow Cytometry. Immunohistochemistry on frozen sections. Recommended Positive Control: placenta, seminoma
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Placental membrane
Specificity	SM2070P recognises placental alkaline phosphate, a 67kD isoform expressed in trophoblast cells of normal human placenta, in seminomas and in ovarian carcinoma. The H17E2 antibody has been widely used in immunolocalisation studies of germ cell tumours and may also be used in ELISA based assays for the measurement of soluble PLAP.
Isotype	IgG1
Formulation	PBS containing 0.09 % Sodium State: Aff - Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	alkaline phosphatase, placental
Database Link	Entrez Gene 250 Human UniProt ID P05187
Background	Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.
Synonyms	PLAP-1, Alkaline phosphatase Regan isozyme
Reference Data

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