MCP3 (CCL7) Mouse Monoclonal Antibody [Clone ID: h.mcp.3]

Specifications

Product Data
Clone Name	h.mcp.3
Applications	ELISA, FN
Recommend Dilution	ELISA: 1/1000. Functional Assays: 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human MCP-3 (Macrophage Chemoattractant Protein-3) Spleen cells from immunised C3H/HeJ mice were fused with cells of a mouse myeloma cell line.
Specificity	This antibody specifically recognises MCP-3, also known as CCL7. No cross reactivity is observed with MCP-1, MCP-2 or other structurally related chemokines.
Isotype	IgG1
Formulation	PBS, pH7.2 State: Azide Free State: Lyophilized purified IgG
Reconstitution Method	Restore with 0.5 ml distilled water. Note: Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently vortexed after reconstitution and microcentrifuged before use.
Concentration	lot specific
Purification	Affinity chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody at -20°C. Avoid repeated freezing and thawing.
Gene Name	C-C motif chemokine ligand 7
Database Link	Entrez Gene 6354 Human UniProt ID P80098
Background	This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
Synonyms	Small-inducible cytokine A7, CCL-7, MCP-3, C-C motif chemokine 7, SCYA6, SCYA7, NC28
Reference Data

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