TRIM (TRAT1) (29-186) Mouse Monoclonal Antibody [Clone ID: TRIM-04]

Specifications

Product Data
Clone Name	TRIM-04
Applications	FC, IP, WB
Recommend Dilution	Immunoprecipitation. Western Blot (Non reducing conditions). Flow Cytometry (Intracellular staining):Recommended dilution: 1-4 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant intracellular domain (aa 29-186) of Human TRIM
Specificity	The antibody TRIM-04 reacts with T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
Isotype	IgG2a
Formulation	PBS, pH~7.4 State: Purified State: Liquid purified Ig fraction  (> 95% pure by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	T cell receptor associated transmembrane adaptor 1
Database Link	Entrez Gene 50852 Human UniProt ID Q6PIZ9
Background	TRIM (T cell receptor-interacting molecule) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
Synonyms	TCRIM
Reference Data

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