Adiponectin (ADIPOQ) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Embedded Sections (10 µg/ml). Positive Control: Rat brain. Western blot (1.0-2.0 µg/ml): This antibody detects a band of approximately 26.4kDa in human HL60 cell lysates. Immunocytochemistry. Flow cytometry.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 15 amino acid peptide located near human Adiponectin carboxy-terminus.
Specificity	This antibody recognises an epitope within the C-terminal region (CT) of the 244 amino acid protein Adiponectin.
Formulation	Phosphate buffered saline, pH 7.2 with 0.02% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Affinity Chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Gene Name	adiponectin, C1Q and collagen domain containing
Database Link	Entrez Gene 9370 Human UniProt ID Q15848
Background	Adiponectin (also known as Acrp30), is a major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, Adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of Adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis.
Synonyms	ADIPOQ, ACDC, ACRP30, APM1, GBP28
Reference Data

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