Dysbindin (DTNBP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:10~50
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	This Dtnbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human Dtnbp1.
Isotype	IgG
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dystrobrevin binding protein 1
Database Link	NP_115498 Entrez Gene 94245 MouseEntrez Gene 84062 Human UniProt ID Q96EV8
Background	Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this protein are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
Synonyms	BLOC1S8; DBND; HPS7; My031; SDY
Reference Data
Protein Families	Druggable Genome

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