BNIP3L Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, IP, WB
Recommend Dilution	IF: 1:50~100, WB: 1:1000, IHC: 1:50~100
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	This BNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-187 amino acids from human BNIP3.
Isotype	Ig
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21541 Da
Gene Name	BCL2/adenovirus E1B 19kDa interacting protein 3-like
Database Link	NP_004322 Entrez Gene 12177 MouseEntrez Gene 665 Human UniProt ID O60238
Background	NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Synonyms	BNIP3a; NIX
Reference Data
Protein Families	Druggable Genome, Transmembrane

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