NCOA1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Pig
Host	Rabbit
Clonality	Polyclonal
Immunogen	This SRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the N-terminal region of human SRC1.
Isotype	Ig
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	156757 Da
Gene Name	nuclear receptor coactivator 1
Database Link	NP_003734 Entrez Gene 8648 Human UniProt ID Q15788
Background	SRC1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. This protein binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.
Synonyms	bHLHe42; bHLHe74; F-SRC-1; KAT13A; RIP160; SRC1
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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