RNF2 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:4,000. WB: 0.3-1µg/ml.
Reactivity	Human, Mouse, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-PMELYYAPTKEHK, from the C Terminus of the protein sequence according to NP_009143.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41281 Da
Gene Name	ring finger protein 2
Database Link	NP_009143 Entrez Gene 19821 MouseEntrez Gene 480042 DogEntrez Gene 6045 Human UniProt ID Q99496
Background	Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq]
Synonyms	BAP-1; BAP1; DING; HIPI3; RING1B; RING2
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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