CD2BP2 Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 0.3-1ug/mL, IHC: 5-10ug/mL
Reactivity	Human, Mouse, Rat, Dog, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence PKRKVTFQGVGDE-C, from the N Terminus of the protein sequence according to NP_006101.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD2 (cytoplasmic tail) binding protein 2
Database Link	NP_006101 Entrez Gene 70233 MouseEntrez Gene 293505 RatEntrez Gene 489937 DogEntrez Gene 10421 Human UniProt ID O95400
Background	This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq]
Synonyms	FWP010; LIN1; PPP1R59; Snu40; U5-52K
Reference Data

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