AICDA Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:1,000. WB: 0.1-0.3µg/ml.
Reactivity	Human, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence RRKFLYQFKNVR-C, from the N Terminus of the protein sequence according to NP_065712.1.
Isotype	IgG
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	activation-induced cytidine deaminase
Database Link	NP_065712 Entrez Gene 57379 Human UniProt ID Q9GZX7
Background	RNA-editing deaminase involved in somatic hypermutation, gene conversion, and class-switch recombination. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses
Synonyms	AID; ARP2; CDA2; HEL-S-284; HIGM2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Primary immunodeficiency

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