FBXO43 Goat Polyclonal Antibody

Specifications

Product Data
Recommend Dilution	WB: 1-3ug/ml.
Reactivity	Mouse, Rat, Human, Dog, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-PGSAQSKRNLKRL, from the C Terminus of the protein sequence according to NP_001070996.1; NP_001025031.2.
Isotype	IgG
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	F-box protein 43
Database Link	NP_001025031 Entrez Gene 78803 MouseEntrez Gene 315034 RatEntrez Gene 481982 DogEntrez Gene 286151 Human UniProt ID Q4G163
Background	Members of the F-box protein family, such as FBXO43, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM]
Synonyms	EMI2; ERP1; FBX43
Reference Data
Protein Pathways	Oocyte meiosis

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