VPS37C Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 1 and 46 of VPS37C (Uniprot ID#A5D8V6)
Isotype	IgG
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39 kDa
Gene Name	VPS37C, ESCRT-I subunit
Database Link	NP_060436 Entrez Gene 107305 MouseEntrez Gene 308178 RatEntrez Gene 55048 Human UniProt ID A5D8V6
Background	VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]). [supplied by OMIM]
Synonyms	FLJ20847
Note	Seq homology of immunogen across species: Mouse (87%), Rat (87%), Bovine (87%)
Reference Data
Protein Pathways	Endocytosis

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