EIF2B2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Mouse, Chicken, Rabbit, Rat, Zebrafish, Bovine, X. tropicalis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 88 and 323 of EIF2B beta (Uniprot ID#P49770)
Isotype	IgG
Formulation	0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39 kDa
Gene Name	eukaryotic translation initiation factor 2B subunit beta
Database Link	NP_055054 Entrez Gene 84005 RatEntrez Gene 217715 MouseEntrez Gene 8892 Human UniProt ID P49770
Background	Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits. EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP. [supplied by OMIM]
Synonyms	EIF-2Bbeta; EIF2B
Note	Seq homology of immunogen across species: Mouse (96%), Chicken (90%), Rabbit (98%), Rat (94%), Zebrafish (85%), Bovine (98%), Xenopus tropicalis (87%)
Reference Data

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